Weihsueh A. Chiu: search on Z-Library

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1

Systematic reviews and meta-analyses of human and animal evidence of prenatal diethylhexyl phthalate exposure and changes in male anogenital distance

Dorman, David C., Chiu, Weihsueh, Hales, Barbara F., Hauser, Russ, Johnson, Kamin J., Mantus, Ellen, Martel, Susan, Robinson, Karen A., Rooney, Andrew A., Rudel, Ruthann, Sathyanarayana, Sheela, Schan

Journal:

Journal of Toxicology and Environmental Health Part B

Year:

2018

Language:

english

File:

PDF, 2.62 MB

english, 2018

2

Thorough QT/QTc in a Dish: An In Vitro Human Model That Accurately Predicts Clinical Concentration-QTc Relationships

Blanchette, Alexander D., Grimm, Fabian A., Dalaijamts, Chimedullam, Hsieh, Nan-Hung, Ferguson, Kyle, Luo, Yu-Syuan, Rusyn, Ivan, Chiu, Weihsueh A.

Journal:

Clinical Pharmacology & Therapeutics

Year:

2018

Language:

english

File:

PDF, 1.79 MB

english, 2018

3

Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes

Burnett, Sarah D., Blanchette, Alexander D., Grimm, Fabian A., House, John S., Reif, David M., Wright, Fred A., Chiu, Weihsueh A., Rusyn, Ivan

Journal:

Toxicology and Applied Pharmacology

Year:

2019

Language:

english

File:

PDF, 7.60 MB

english, 2019

4

Evaluation of physiologically based pharmacokinetic models for use in risk assessment

Weihsueh A. Chiu, Hugh A. Barton, Robert S. DeWoskin, Paul Schlosser, Chad M. Thompson, Babasaheb Sonawane, John C. Lipscomb, Kannan Krishnan

Journal:

Journal of Applied Toxicology

Year:

2007

Language:

english

File:

PDF, 191 KB

english, 2007

5

Trichloroacetic acid: Updated estimates of its bioavailability and its contribution to trichloroethylene-induced mouse hepatomegaly

Weihsueh A. Chiu

Journal:

Year:

2011

Language:

english

File:

PDF, 569 KB

english, 2011

6

Revisiting the population toxicokinetics of tetrachloroethylene

Weihsueh A. Chiu, Frédéric Y. Bois

Journal:

Archives of Toxicology

Year:

2006

Language:

english

File:

PDF, 564 KB

english, 2006

7

Revisiting the population toxicokinetics of tetrachloroethylene

Weihsueh A. Chiu, Frédéric Y. Bois

Journal:

Archives of Toxicology

Year:

2006

Language:

english

File:

PDF, 105 KB

english, 2006

8

Response

Louis Anthony Cox Jr., Weihsueh A. Chiu, David M. Hassenzahl, Daniel M. Kammen

Journal:

Year:

2000

Language:

english

File:

PDF, 33 KB

english, 2000

9

A Comparison of Regulatory Implications of Traditional and Exact Two-Stage Dose-Response Models

Weihsueh A. Chiu, David M. Hassenzahl, Daniel M. Kammen

Journal:

Year:

1999

Language:

english

File:

PDF, 587 KB

english, 1999

10

Steady-State Solutions to PBPK Models and Their Applications to Risk Assessment I: Route-to-Route Extrapolation of Volatile Chemicals

Weihsueh A. Chiu, Paul White

Journal:

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

11

Steady-State Solutions to PBPK Models and Their Applications to Risk Assessment I: Route-to-Route Extrapolation of Volatile Chemicals—Authors' Response to Letter by Dr. Kenneth Bogen

Weihsueh A. Chiu, Paul White

Journal:

Year:

2006

Language:

english

File:

PDF, 78 KB

english, 2006

12

A Comparison of Regulatory Implications of Traditional and Exact Two-Stage Dose–Response Models

Weihsueh A. Chiu, David M. Hassenzahl, Daniel M. Kammen

Journal:

Year:

1999

Language:

english

File:

PDF, 90 KB

english, 1999

13

Using Copulas to Introduce Dependence in Dose-Response Modeling of Multiple Binary Endpoints

Weihsueh A. Chiu, Kenny S. Crump

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2012

Language:

english

File:

PDF, 435 KB

english, 2012

14

Characterizing uncertainty and population variability in the toxicokinetics of trichloroethylene and metabolites in mice, rats, and humans using an updated database, physiologically based pharmacokinetic (PBPK) model, and Bayesian approach

Weihsueh A. Chiu, Miles S. Okino, Marina V. Evans

Journal:

Toxicology and Applied Pharmacology

Year:

2009

Language:

english

File:

PDF, 2.34 MB

english, 2009

15

Development and evaluation of a harmonized physiologically based pharmacokinetic (PBPK) model for perchloroethylene toxicokinetics in mice, rats, and humans

Weihsueh A. Chiu, Gary L. Ginsberg

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.50 MB

english, 2011

16

Bayesian population analysis of a harmonized physiologically based pharmacokinetic model of trichloroethylene and its metabolites

C. Eric Hack, Weihsueh A. Chiu, Q. Jay Zhao, Harvey J. Clewell

Journal:

Regulatory Toxicology and Pharmacology

Year:

2006

Language:

english

File:

PDF, 1.38 MB

english, 2006

17

An Approximate Method for Population Toxicokinetic Analysis With Aggregated Data

Weihsueh A. Chiu, Frédéric Y. Bois

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2007

Language:

english

File:

PDF, 237 KB

english, 2007

18

Statistical inferences from serially correlated methylene chloride data

Martin Klein, Nagaraj Neerchal, Bimal Sinha, Weihsueh Chiu, Paul White

Journal:

Year:

2012

Language:

english

File:

PDF, 745 KB

english, 2012

19

Trichloroethylene biotransformation and its role in mutagenicity, carcinogenicity and target organ toxicity

Lash, Lawrence H., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan

Journal:

Mutation Research/Reviews in Mutation Research

Year:

2014

Language:

english

File:

PDF, 755 KB

english, 2014

20

Trichloroethylene: Mechanistic, epidemiologic and other supporting evidence of carcinogenic hazard

Rusyn, Ivan, Chiu, Weihsueh A., Lash, Lawrence H., Kromhout, Hans, Hansen, Johnni, Guyton, Kathryn Z.

Journal:

Pharmacology & Therapeutics

Year:

2014

Language:

english

File:

PDF, 532 KB

english, 2014

21

Utilizing toxicogenomic data to understand chemical mechanism of action in risk assessment

Wilson, Vickie S., Keshava, Nagalakshmi, Hester, Susan, Segal, Deborah, Chiu, Weihsueh, Thompson, Chad M., Euling, Susan Y.

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 447 KB

english, 2013

22

Approaches to advancing quantitative human health risk assessment of environmental chemicals in the post-genomic era

Chiu, Weihsueh A., Euling, Susan Y., Scott, Cheryl Siegel, Subramaniam, Ravi P.

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 878 KB

english, 2013

23

A systematic approach for identifying and presenting mechanistic evidence in human health assessments

Kushman, Mary E., Kraft, Andrew D., Guyton, Kathryn Z., Chiu, Weihsueh A., Makris, Susan L., Rusyn, Ivan

Journal:

Regulatory Toxicology and Pharmacology

Year:

2013

Language:

english

File:

PDF, 2.47 MB

english, 2013

24

An approach for integrating toxicogenomic data in risk assessment: The dibutyl phthalate case study

Euling, Susan Y., Thompson, Chad M., Chiu, Weihsueh A., Benson, Robert

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.12 MB

english, 2013

25

PPARα and TCE: Keshava et al. Respond

Nagalakshmi Keshava, Weihsueh A. Chiu and Jane C. Caldwell

Journal:

Environmental Health Perspectives

Year:

2007

Language:

english

File:

PDF, 485 KB

english, 2007

26

A Reexamination of the PPAR-α Activation Mode of Action as a Basis for Assessing Human Cancer Risks of Environmental Contaminants

Kathryn Z. Guyton, Weihsueh A. Chiu, Thomas F. Bateson, Jennifer Jinot, Cheryl Siegel Scott, Rebecca C. Brown and Jane C. Caldwell

Journal:

Environmental Health Perspectives

Year:

2009

Language:

english

File:

PDF, 2.22 MB

english, 2009

27

Trichloroethylene Cancer Epidemiology: A Consideration of Select Issues

Cheryl Siegel Scott and Weihsueh A. Chiu

Journal:

Environmental Health Perspectives

Year:

2006

Language:

english

File:

PDF, 2.18 MB

english, 2006

28

Approaches to Human Health Risk Assessment Based on the Signal-To-Noise Crossover Dose

Weihsueh A. Chiu, Kathryn Z. Guyton, Karen Hogan and Jennifer Jinot

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 318 KB

english, 2012

29

What Role for Biologically Based Dose—Response Models in Estimating Low-Dose Risk?

Kenny S. Crump, Chao Chen, Weihsueh A. Chiu, Thomas A. Louis, Christopher J. Portier, Ravi P. Subramaniam and Paul D. White

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 1.10 MB

english, 2010

30

Issues in Using Human Variability Distributions to Estimate Low-Dose Risk

Kenny S. Crump, Weihsueh A. Chiu and Ravi P. Subramaniam

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 1.79 MB

english, 2010

31

Key Scientific Issues in the Health Risk Assessment of Trichloroethylene

Weihsueh A. Chiu, Jane C. Caldwell, Nagalakshmi Keshava and Cheryl Siegel Scott

Journal:

Environmental Health Perspectives

Year:

2006

Language:

english

File:

PDF, 1.24 MB

english, 2006

32

High-to-Low Dose Extrapolation: Issues and Approaches

Chiu, Weihsueh A., Chen, Chao, Hogan, Karen, Lipscomb, John C., Scott, Cheryl Siegel, Subramaniam, Ravi

Journal:

Human and Ecological Risk Assessment An International Journal

Year:

2007

Language:

english

File:

PDF, 70 KB

english, 2007

33

Comments on Article “Applying Mode-of-Action and Pharmacokinetic Considerations in Contemporary Cancer Risk Assessments: An Example with Trichloroethylene” by Clewell and Andersen

Caldwell, Jane C., Evans, Marina V., Marcus, Allan H., Scott, Cheryl Siegel, Chiu, Weihsueh A., Okino, Miles S., Preuss, Peter W.

Journal:

Critical Reviews in Toxicology

Year:

2006

Language:

english

File:

PDF, 71 KB

english, 2006

34

Approaches for Applications of Physiologically Based Pharmacokinetic Models in Risk Assessment

Thompson, Chad M., Sonawane, Babasaheb, Barton, Hugh A., DeWoskin, Robert S., Lipscomb, John C., Schlosser, Paul, Chiu, Weihsueh A., Krishnan, Kannan

Journal:

Journal of Toxicology and Environmental Health Part B

Year:

2008

Language:

english

File:

PDF, 522 KB

english, 2008

35

Human Health Effects of Trichloroethylene: Key Findings and Scientific Issues

Chiu, Weihsueh A., Jinot, Jennifer, Scott, Cheryl Siegel, Makris, Susan L., Cooper, Glinda S., Dzubow, Rebecca C., Bale, Ambuja S., Evans, Marina V., Guyton, Kathryn Z., Keshava, Nagalakshmi, Lipscomb

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 566 KB

english, 2012

36

Trichloroethylene Cancer Epidemiology: A Consideration of Select Issues

Scott, Cheryl Siegel, Chiu, Weihsueh A.

Journal:

Environmental Health Perspectives

Year:

2006

Language:

english

File:

PDF, 143 KB

english, 2006

37

Standardizing Benchmark Dose Calculations to Improve Science-Based Decisions in Human Health Assessments

Wignall, Jessica A., Shapiro, Andrew J., Wright, Fred A., Woodruff, Tracey J., Chiu, Weihsueh A., Guyton, Kathryn Z., Rusyn, Ivan

Journal:

Environmental Health Perspectives

Year:

2014

Language:

english

File:

PDF, 582 KB

english, 2014

38

A Reexamination of the PPAR-α Activation Mode of Action as a Basis for Assessing Human Cancer Risks of Environmental Contaminants

Guyton, Kathryn Z., Chiu, Weihsueh A., Bateson, Thomas F., Jinot, Jennifer, Siegel Scott, Cheryl, Brown, Rebecca C., Caldwell, Jane C.

Journal:

Environmental Health Perspectives

Year:

2009

Language:

english

File:

PDF, 927 KB

english, 2009

39

Issues in the Pharmacokinetics of Trichloroethylene and Its Metabolites

Chiu, Weihsueh A., Okino, Miles S., Lipscomb, John C., Evans, Marina V.

Journal:

Environmental Health Perspectives

Year:

2006

Language:

english

File:

PDF, 156 KB

english, 2006

40

A Framework for the Next Generation of Risk Science

Krewski, Daniel, Westphal, Margit, Andersen, Melvin E., Paoli, Gregory M., Chiu, Weihsueh A., Al-Zoughool, Mustafa, Croteau, Maxine C., Burgoon, Lyle D., Cote, Ila

Journal:

Environmental Health Perspectives

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

41

Key Scientific Issues in the Health Risk Assessment of Trichloroethylene

Chiu, Weihsueh A., Caldwell, Jane C., Keshava, Nagalakshmi, Scott, Cheryl Siegel

Journal:

Environmental Health Perspectives

Year:

2006

Language:

english

File:

PDF, 119 KB

english, 2006

42

Issues in Using Human Variability Distributions to Estimate Low-Dose Risk

Crump, Kenny S., Chiu, Weihsueh A., Subramaniam, Ravi P.

Journal:

Environmental Health Perspectives

Year:

2009

Language:

english

File:

PDF, 851 KB

english, 2009

43

Approaches to Human Health Risk Assessment Based on the Signal-To-Noise Crossover Dose

Chiu, Weihsueh A., Guyton, Kathryn Z., Hogan, Karen, Jinot, Jennifer

Journal:

Environmental Health Perspectives

Year:

2012

Language:

english

File:

PDF, 75 KB

english, 2012

44

Population-Based in Vitro Hazard and Concentration–Response Assessment of Chemicals: The 1000 Genomes High-Throughput Screening Study

Abdo, Nour, Xia, Menghang, Brown, Chad C., Kosyk, Oksana, Huang, Ruili, Sakamuru, Srilatha, Zhou, Yi-Hui, Jack, John, Gallins, Paul, Xia, Kai, Li, Yun, Chiu, Weihsueh A., Motsinger-Reif, Alison, Austi

Journal:

Environmental Health Perspectives

Year:

2015

Language:

english

File:

PDF, 1.57 MB

english, 2015

45

What Role for Biologically Based Dose–Response Models in Estimating Low-Dose Risk?

Crump, Kenny S., Chen, Chao, Chiu, Weihsueh A., Louis, Thomas A., Portier, Christopher J., Subramaniam, Ravi P., White, Paul D.

Journal:

Environmental Health Perspectives

Year:

2010

Language:

english

File:

PDF, 234 KB

english, 2010

46

Development and application of a rat PBPK model to elucidate kidney and liver effects induced by ETBE and tert-butanol

Salazar, Keith D., Brinkerhoff, Christopher J., Lee, Janice S., Chiu, Weihsueh A.

Journal:

Toxicology and Applied Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.04 MB

english, 2015

47

Issues in the Pharmacokinetics of Trichloroethylene and Its Metabolites

Weihsueh A. Chiu, Miles S. Okino, John C. Lipscomb and Marina V. Evans

Journal:

Environmental Health Perspectives

Year:

2006

Language:

english

File:

PDF, 1.92 MB

english, 2006

48

An Approximate Method for Population Toxicokinetic Analysis with Aggregated Data

Weihsueh A. Chiu and Frédéric Y. Bois

Journal:

Journal of Agricultural, Biological, and Environmental Statistics

Year:

2007

Language:

english

File:

PDF, 1.64 MB

english, 2007

49

Management of sewage sludge and ash containing radioactive materials

Bachmaier, James T., Aiello, Kevin, Bastian, Robert K., Cheng, Jing Jy, Chiu, Weihsueh A., Goodman, Jenny, Hogan, Rosemary, Jones, Andrea R., Kamboj, Sunita, Lenhart, Thomas, Ott, William R., Rubin, A

Journal:

International Journal of Environment and Waste Management

Year:

2007

Language:

english

File:

PDF, 393 KB

english, 2007

50

Combining Wilkinson Microwave Anisotropy Probe and Sloan Digital Sky Survey Quasar Data on Reionization Constrains Cosmological Parameters and Star Formation Efficiency

Chiu, Weihsueh A., Fan, Xiaohui, Ostriker, Jeremiah P.

Journal:

The Astrophysical Journal

Year:

2003

Language:

english

File:

PDF, 371 KB

english, 2003